Medicine (Baltimore). 2021 Apr 9;100(14):e25397. doi: 10.1097/MD.0000000000025397.ABSTRACTDecision-making to stop cancer treatment in patients with advanced cancer is stressful, and it significantly influences subsequent end-of-life palliative treatment. However, little is known about the extent to which the patient’s self-decisions influenced the prognostic period. This study focused on the patient’s self-decision and investigated the impact of the self-decision to stop cancer treatment on their post-cancer treatment survival period and place of death.We retrospectively analyzed 167 cases of advanced genitourinary cancer patients (kidney cancer: 42; bladder cancer: 68; prostate cancer: 57) treated at the University of Fukui Hospital (UFH), who later died because…
Origen: Impact of self-decision to stop cancer treatment on advanced genitourinary cancer patients – PubMed

Anticancer Res. 2021 Apr;41(4):2111-2115. doi: 10.21873/anticanres.14982.ABSTRACTBACKGROUND/AIM: It has been hypothesized that many, or even most cancers, utilize a unique immunomodulatory protein, called the progesterone induced blocking factor (PIBF) to allow spread of the cancer. Support for this concept has been provided by cancer cell line studies showing that PIBF is produced by these cancer cells and mifepristone suppresses this protein and inhibits proliferation of these cells. Furthermore, controlled murine studies with several spontaneous different types of cancer showed a clear beneficial effect of mifepristone over placebo control. Finally, there have been a variety of anecdotal reports showing efficacy of mifepristone…
Origen: Palliative Benefits of Oral Mifepristone for the Treatment of Metastatic Fibroblastic Osteosarcoma – PubMed

Anticancer Res. 2021 Apr;41(4):1971-1974. doi: 10.21873/anticanres.14964.ABSTRACTBACKGROUND/AIM: Oncological care has faced several challenges during the COVID-19 pandemic, e.g. treatment delay and worsening symptoms. Patient-reported anxiety, depression and sleep quality might have changed due to these special circumstances. Therefore, we analyzed the symptom burden of patients treated with palliative radiotherapy at our center.PATIENTS AND METHODS: A retrospective study was performed of 50 consecutive patients and the results were compared to those obtained in a previous pre-COVID study. The Edmonton Symptom Assessment Scale was employed to assess the preradiotherapy symptoms.RESULTS: The highest mean scores were reported for pain in activity (3.2) and dry…
Origen: Symptom Burden in Patients Treated With Palliative Radiotherapy Before and During the COVID-19 Pandemic – PubMed

Int J Environ Res Public Health. 2021 Mar 24;18(7):3358. doi: 10.3390/ijerph18073358.ABSTRACTNurses working in palliative care are at risk of burnout. The Copenhagen Burnout Inventory was used to determine burnout levels of nurses working in the Portuguese national network of palliative care. We evaluated the contribution of personal, work, and COVID-19 variables in three burnout subclasses: personal, work, and patient-related. A cross-sectional, exploratory, and quantitative design was employed and participants were sampled using convenience and snowball technique. An online survey was conducted and 153 nurses participated in our study. Socio-demographic characterization was conducted, levels of burnout and determinants were explored through…
Origen: Burnout Determinants among Nurses Working in Palliative Care during the Coronavirus Disease 2019 Pandemic – PubMed

Gan To Kagaku Ryoho. 2021 Mar;48(3):413-415.ABSTRACTA 50s-year-old man was admitted to our hospital because of abdominal pain and vomitting. CT showed a thickened wall of the sigmoid colon, marked enlargement of the oral side, and a 30 mm tumor on the left lateral section of the liver. We diagnosed colonic obstruction due to sigmoid colon cancer with liver metastasis. We failed to place a colonic stent for decompression, so we performed a colostomy using the cecum. An exploratory laparoscopy was performed instead of curative surgery due to peritoneal disseminations, followed by chemotherapy and molecular targeted therapy. Although primary lesion, liver…
Origen: A Case of Unresectable Colorectal Cancer with Complete Remission after Palliative Surgery Due to Continued Pharmacotherapy – PubMed