BMJ Open. 2023 Nov 24;13(11):e073835. doi: 10.1136/bmjopen-2023-073835.ABSTRACTINTRODUCTION: Adolescence and early adulthood are often critical periods of sexual development. The discovery of sexual intercourse can lead to sexual risk-taking which may impact the incidence of sexually transmitted infections (STIs) and unwanted pregnancies. Despite available sexual health services on Reunion Island, sexual health indicators for adolescents are very poor showing a high number of teenage pregnancies and abortions, low use of contraception and an upsurge of STIs. In contrast, this French region is equipped with many services and resources that enable young adults to make informed sexual health choices. This study protocol…
Origen: Experiences of adolescents using sexual health services on Reunion Island: protocol for a qualitative phenomenological study – PubMed

Curr Oncol. 2023 Nov 13;30(11):9895-9905. doi: 10.3390/curroncol30110719.ABSTRACTRadiotherapy (RT) and electrochemotherapy (ECT) are established local treatments for cancer. While effective, both therapies have limitations, especially in treating bulky and poorly oxygenated tumors. ECT has emerged as a promising palliative treatment, raising interest in exploring its combination with RT to enhance tumor response. However, the potential benefits and challenges of combining these treatments remain unclear. A systematic review was conducted following PRISMA guidelines. PubMed, Scopus, and Cochrane libraries were searched. Studies were screened and selected based on predefined inclusion and exclusion criteria. Ten studies were included, comprising in vitro and in vivo…
Origen: Combination of Electrochemotherapy with Radiotherapy: A Comprehensive, Systematic, PRISMA-Compliant Review of Efficacy and Potential Radiosensitizing Effects in Tumor Control – PubMed

Sci Rep. 2023 Nov 23;13(1):20557. doi: 10.1038/s41598-023-47622-7.ABSTRACTWe present the first data-driven pediatric model that explains cranial sutural growth in the pediatric population. We segmented the cranial bones in the neurocranium from the cross-sectional CT images of 2068 normative subjects (age 0-10 years), and we used a 2D manifold-based cranial representation to establish local anatomical correspondences between subjects guided by the location of the cranial sutures. We designed a diffeomorphic spatiotemporal model of cranial bone development as a function of local sutural growth rates, and we inferred its parameters statistically from our cross-sectional dataset. We used the constructed model to predict…
Origen: Data-driven cranial suture growth model enables predicting phenotypes of craniosynostosis – PubMed

Ned Tijdschr Geneeskd. 2023 Nov 22;167:D7809.ABSTRACTPalliative care: •is an approach that improves the quality of life of patients and their families who are facing problems associated with life-threatening illness or frailty; •is not restricted to terminal care; •is started early in the trajectory of all life-threatening illnesses (oncological and non-oncological); •requires specific knowledge, communication skills and attitude, and an interdisciplinary approach; •requires a systematic approach for complaints and problems in all domains; •addresses all domains: physical, psychological, social and spiritual; •looks for a balance between disease-oriented and symptom-oriented treatment; •includes advance care planning and a careful exploration of a death…
Origen: More focus on palliative care – PubMed

BMJ. 2023 Nov 21;383:2648. doi: 10.1136/bmj.p2648.NO ABSTRACTPMID:37989503 | DOI:10.1136/bmj.p2648
Origen: Advocating for patients: the GP and facilitator in palliative care – PubMed