BMJ Open. 2025 Jun 12;15(6):e084476. doi: 10.1136/bmjopen-2024-084476.ABSTRACTOBJECTIVES: To determine if carer administration of as-needed subcutaneous medication for common breakthrough symptoms in people dying at home is feasible and acceptable in the UK, and if it would be feasible to test this intervention in a future definitive randomised controlled trial.DESIGN: We conducted a two-arm, parallel-group, individually randomised, open pilot trial of the intervention versus usual care, with a 1:1 allocation ratio, using convergent mixed methods.SETTING: Home-based care without 24/7 paid care provision, in three UK sites.PARTICIPANTS: Participants were dyads of adult patients and carers: patients in the last weeks of their…
Origen: Carer administration of as-needed subcutaneous medication for breakthrough symptoms in people dying at home: the CARiAD feasibility RCT – PubMed

World J Gastroenterol. 2025 May 21;31(19):101913. doi: 10.3748/wjg.v31.i19.101913.ABSTRACTBACKGROUND: Endoscopic bilateral biliary drainage is a first line palliative treatment for unresectable malignant hilar biliary obstruction (MHBO) but remains technically challenging. The emergence of self-expandable metallic stents carried by an ultra-thin (6 Fr or smaller) delivery system now permits simultaneous bilateral stent placement. To date, only a few studies have compared this new method with conventional sequential bilateral stenting.AIM: To evaluate a possible superiority of simultaneous «side by side» (SBS) biliary drainage in unresectable MHBO.METHODS: We identified 135 patients who benefited from bilateral drainage using uncovered self-expandable metallic stents between 2010 and…
Origen: Direct comparison of simultaneous and sequential endoscopic metallic bilateral stenting in malignant hilar biliary obstruction – PubMed

BMC Palliat Care. 2025 Jun 11;24(1):164. doi: 10.1186/s12904-025-01777-4.ABSTRACTBACKGROUND: Palliative sedation is the monitored use of medications intended to reduce consciousness to relieve the burden of otherwise intractable suffering. Since 2016, the French Leonetti-Claeys law has granted patients the right to receive continuous deep sedation until death (CDSUD) for some indications. There are relatively few data in the literature assessing sedation practices in palliative care units (PCUs).METHODS: This study aimed to compare sedation practices in six French PCUs, analyzing the frequency, types of sedation (CDSUD vs. proportional sedation), and use of sedative medications during the last 72 h of life. This…
Origen: Variability of sedation practices in palliative care unit in France: a six units retrospective analysis – PubMed

Arch Esp Urol. 2025 May;78(4):451-458. doi: 10.56434/j.arch.esp.urol.20257804.60.ABSTRACTBACKGROUND: This retrospective study aimed to evaluate the effect of meaning-centred group psychotherapy (MCGP) on patients with advanced urologic cancer.METHODS: A retrospective analysis was conducted on the medical records of patients with advanced urological system tumours who visited our hospital from January 2022 to January 2024. Patients were divided into a conventional group and an MCGP group on the basis of the type of nursing care they received. Both groups underwent nursing care for one month, and the Meaning in Life Questionnaire (MLQ), Herth Hope Index (HHI), Self-Perceived Burden Scale (SPBS) and Hospital Anxiety…
Origen: The Impact of Meaning-Centred Group Psychotherapy Conducted by a Palliative Care Team on Patients with Advanced Urological System Tumours: A Single-Centre Retrospective Study – PubMed

Age Ageing. 2025 May 31;54(6):afaf163. doi: 10.1093/ageing/afaf163.ABSTRACTBACKGROUND: Chronic conditions like heart disease and dementia have surpassed cancer as leading causes of death in aging populations. Non-cancer patients, despite similar palliative care needs, often face delayed initiation or limited access. This study investigated the proximity of palliative care initiation to death among older adults with different diagnoses and influencing factors.METHODS: This cross-sectional study used Taiwan’s National Health Insurance and Multiple Causes of Death databases (2010-2020), including individuals aged ≥65 who received specialist palliative care before death. Multinomial logistic regression analysed the association of cancer status and year of death with the…
Origen: Impact of disease type and temporal trends on the proximity of palliative care initiation to death in older adults: a population-based study – PubMed