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Effects of oral intake, symptom severity, and sex difference on cancer patient prognosis

Support Care Cancer. 2025 Jan 9;33(2):84. doi: 10.1007/s00520-024-09124-8.ABSTRACTPURPOSE: For cancer patients, prognostication by physicians constitutes a fundamental basis of decision-making to manage the cancer journey, especially with advanced stages of cancer. Various tools such as the palliative prognostic index (PPI) have been established to estimate patient survival. Such reliable and widely applied tools unfortunately provide unexpected results of prognosis predictions in some cases. To support disease-related decision-making, this study explores factors associated with prognosis prediction outliers in patients with advanced cancer in palliative care units (PCUs).METHODS: For this retrospective observational study conducted at a PCU, we surveyed medical records of…
Origen: Effects of oral intake, symptom severity, and sex difference on cancer patient prognosis – PubMed

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Observational Study of Best Supportive Care With or Without Oral Capecitabine in Patients With Metastatic Gallbladder Carcinoma at a Tertiary Center in India

JCO Glob Oncol. 2025 Jan;11:e2400341. doi: 10.1200/GO-24-00341. Epub 2025 Jan 9.ABSTRACTPURPOSE: To compare overall survival (OS), toxicity, and quality of life (QOL) in patients with metastatic gallbladder cancer receiving oral capecitabine (X) with best supportive care (BSC) and BSC alone.MATERIALS AND METHODS: Patients with metastatic gallbladder cancer and Karnofsky Performance Status (KPS) ≥70 were accrued and assigned to either arm A or B. Assignment to these two arms was based on physician/patient discretion. Arm A received oral capecitabine 825 mg/m2 twice a day d1-14, repeated every 3 weeks for six cycles with BSC, and arm B received BSC alone. The…
Origen: Observational Study of Best Supportive Care With or Without Oral Capecitabine in Patients With Metastatic Gallbladder Carcinoma at a Tertiary Center in India – PubMed

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Enhancing oncology patient care: nurses' knowledge, attitudes, and perceived benefits of early palliative integration – a cross-sectional study

BMC Palliat Care. 2025 Jan 9;24(1):7. doi: 10.1186/s12904-025-01648-y.ABSTRACTBACKGROUND: Palliative care aims to improve quality of life for patients with end-stage illnesses by addressing physical, psychological, social and spiritual needs. Early referral to palliative care improves patient outcomes, quality of life and overall survival in a variety type of cancers. This study aimed to assess knowledge, attitudes and perceived benefits of early integration of palliative care among oncology nursing.METHODS: A descriptive cross-sectional study was conducted in public, private, and educational hospitals located in Palestine. Data were collected using paper based self-administered questionnaires from nurses working in hematology, general oncology, and bone…
Origen: Enhancing oncology patient care: nurses' knowledge, attitudes, and perceived benefits of early palliative integration – a cross-sectional study – PubMed

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Dementia Care Research and Psychosocial Factors

Alzheimers Dement. 2024 Dec;20 Suppl 4:e088707. doi: 10.1002/alz.088707.ABSTRACTBACKGROUND: People with dementia have complex palliative care needs including psycho-social, physical and spiritual; however, they are often unmet. It is important to empower people with dementia, family caregivers and professionals to work together to better assess and monitor ongoing needs. This study aimed to co-design and test the feasibility of an integrated model of palliative dementia care to support holistic assessment and decision making for care in the community and care homes (assisted living facilities).METHOD: Using a systematic and iterative approach we co-designed the EMBED-Care framework, a holistic assessment and clinical decision…
Origen: Dementia Care Research and Psychosocial Factors – PubMed

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Experiences With End-of-Life Care for Patients With Pre-Existing Severe Mental Disorders, Their Relatives, and Healthcare Professionals

Int J Ment Health Nurs. 2025 Feb;34(1):e13498. doi: 10.1111/inm.13498.ABSTRACTKnowledge is needed about end-of-life care among patients with pre-existing severe mental disorders: Schizophrenia, bipolar disorder, and depression. This study aimed to explore the experiences with end-of-life care for patients with severe mental disorders, their relatives, specialised palliative care nurses and physicians, and general practitioners. Twenty semi-structured interviews were conducted and analysed using reflexive thematic analysis, hereby six interviews with patients, three with relatives, five with general practitioners, and six with specialised palliative healthcare professionals. Patients were selected with help from healthcare professionals. Four main themes were produced: thoughts about the future,…
Origen: Experiences With End-of-Life Care for Patients With Pre-Existing Severe Mental Disorders, Their Relatives, and Healthcare Professionals – PubMed

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