Lasers Med Sci. 2025 Jun 7;40(1):259. doi: 10.1007/s10103-025-04511-x.ABSTRACTThis study aimed to evaluate the efficacy of palliative holmium laser enucleation of the prostate (HoLEP) versus plasma kinetic resection of the prostate (PKRP) in the management of advanced prostate cancer (APC) with concurrent lower urinary tract symptoms (LUTS).A retrospective analysis was conducted from February 2017 to March 2021, which included 41 patients with LUTS from two centers. Of these, 23 patients underwent palliative HoLEP and 18 underwent PKRP. Variables including age, prostate-specific antigen (PSA), prostate volume (V), Gleason Score, clinical staging, International Prostate Symptom Score (IPSS), maximum urinary flow rate (Qmax), functional…
Origen: Comparative evaluation of palliative holmium laser enucleation and plasma kinetic prostate resection in the management of advanced prostate cancer with lower urinary tract symptoms – PubMed

BMC Palliat Care. 2025 Jun 7;24(1):162. doi: 10.1186/s12904-025-01800-8.ABSTRACTOBJECTIVE: The objective of this research is to investigate the efficacy of integrated palliative care in enhancing advanced cancer patients’ quality of life, alleviating pain, and improving psychological well-being through the development of a multidimensional hospice care model.METHODS: This study involved 150 advanced cancer patients who received palliative care at our institution from January 2020 to December 2023. Participants were randomly assigned into two groups: the control group (n = 75) received standard care, while the treatment group (n = 75) received integrated palliative care, which included pain management strategies, psychological support, and…
Origen: Integrated palliative care improves the quality of life of advanced cancer patients – PubMed

Assist Inferm Ric. 2025 Apr-Jun;44(2):52-68. doi: 10.1702/4514.45118.ABSTRACT. Indications to the use of subcutaneous route for fluids and drugs administration: a literature review.INTRODUCTION: Hypodermoclysis is a practice valued in recent years for its safety. However, it continues to be underutilized.OBJECTIVE: To analyze the most recent evidences on the use of hypodermoclysis for fluids and drugs administration, evaluating its efficacy, safety and mode of use on the elderly population and palliative care patients.METHODS: Pubmed, Cochrane Central Register of Controlled Trials and CHINAL databases were searched with the keywords «hypodermoclysis, subcutaneous fluid, subcutaneous infusion»; studies published from 2020 onwards were included.RESULTS: No relevant…
Origen: Indications to the use of subcutaneous route for fluids and drugs administration: a literature review – PubMed

GMS J Med Educ. 2025 Apr 15;42(2):Doc24. doi: 10.3205/zma001748. eCollection 2025.ABSTRACTBACKGROUND: Given demographic changes and a rising prevalence of oncological diseases, understanding the importance of interdisciplinary collaboration and a timely integration of palliative care is crucial. However, both are underrepresented in medical curricula. To address this gap, we introduced a new elective in which students follow the journey of a fictitious patient with prostate cancer from diagnosis until death.METHOD: The elective was conducted through repeated joint meetings by a multi-professional and interdisciplinary (palliative care, urology, radiation oncology, psychosomatic medicine) team. Alongside its development, an outcome evaluation was designed to assess…
Origen: Promoting interdisciplinarity and the timely integration of palliative care through the development and implementation of a blended learning elective for medical students – PubMed

Support Care Cancer. 2025 Jun 5;33(7):540. doi: 10.1007/s00520-025-09587-3.ABSTRACTBACKGROUND AND PURPOSE: Esophageal and gastric cancer patients, with poor prognoses and complex symptom burdens, require comprehensive end-of-life care. This study evaluated the impact of specialist palliative care (SPC) on end-of-life healthcare utilization.MATERIAL AND METHODS: We retrospectively analyzed nationwide healthcare utilization data for all adults who died of esophageal or gastric cancer in Finland in 2019, using National Health and Social Care Registers. Patients were compared based on timing of first SPC contact: early (> 30 days before death) or no/late (≤ 30 days).RESULTS: The cohort included 732 patients (median age 72 years),…
Origen: Specialist palliative care is associated with reduced healthcare utilization in patients with advanced esophageal and gastric cancer: a nationwide register-based study – PubMed