10 important deprescribing articles you should probably know about

Today we come to you with a special literature blog post highlighting 10 key deprescribing articles that together provide an overview of the field of deprescribing – covering the mindset of deprescribing, the complexity of and challenges related to deprescribing in clinical practice, the development and testing of deprescribing interventions, and perspectives of future deprescribing research. We believe each of these 10 articles offer important insights or findings related to deprescribing.

The list is based on careful deliberation between the two of us, after considering a number of worthy candidates. Of course, this list is based on our opinion only and we limited ourselves to 10 articles (which wasn’t easy at all!). We would love to hear your input on our list, so let us know if we have missed any important papers or topics. We will then follow up with a complete list of recommended deprescribing articles for use of all deprescribers out there!


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Duration of palliative care involvement and cancer care aggressiveness near the end of life

Previous studies have found an association between aggressive cancer care and lower quality end of life. Despite international recommendations, late or very late referral to palliative care seems frequent. This study aimed to evaluate the association between the duration of involvement of a palliative care team (PCT), and aggressive cancer care, and to identify factors associated with aggressive cancer care.


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Duration of palliative care before death in international routine practice: a systematic review and meta-analysis

Early provision of palliative care, at least 3–4 months before death, can improve patient quality of life and reduce burdensome treatments and financial costs. However, there is wide variation in the duration of palliative care received before death reported across the research literature. This study aims to determine the duration of time from initiation of palliative care to death for adults receiving palliative care across the international literature.


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Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia A Randomized Clinical Trial

Question  What is the effect of integrated palliative and oncology care (IPC) on patient-reported and end-of-life (EOL) outcomes for patients with acute myeloid leukemia (AML)?


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