BMJ Case Rep. 2021 May 10;14(5):e241070. doi: 10.1136/bcr-2020-241070.ABSTRACTThe approach to metastatic lung cancer has long been focused on palliation therapy and comfort care. Recently, significant subsets of patients who suffer from a limited form of the disease have shown curative outcomes. The oligometastatic disease theory was first introduced in 1995, and since has been applied to many solid tumours. In oligometastatic nonsmall cell lung cancer, current treatment strategies include surgery, radiation therapy and chemotherapy. There is evidence of astounding survival benefits in selected patients treated with immune checkpoint inhibitors. We present three cases with oligometastatic nonsmall cell lung cancer treated…
Origen: Role of immunotherapy in oligometastatic nonsmall cell lung cancer – PubMed

Anticancer Res. 2021 May;41(5):2495-2499. doi: 10.21873/anticanres.15027.ABSTRACTBACKGROUND/AIM: Sino-nasal cancer is rare and often diagnosed at advanced stages. Some patients cannot receive curative treatment and are treated with palliative irradiation. We aimed to identify prognostic factors for survival to facilitate treatment personalization for this group.PATIENTS AND METHODS: Twelve patients treated with palliative radiotherapy for locally advanced sino-nasal cancer were retrospectively analyzed for survival. Ten characteristics were evaluated including age, gender, Karnofsky performance score (KPS), pre-radiotherapy hemoglobin, tumor site, lymph node involvement, histology, equivalent dose in 2 Gy-fractions, completion of radiotherapy and concurrent chemotherapy.RESULTS: On univariate analysis, KPS ≥70 (p<0.001) and completion of…
Origen: Karnofsky Performance Score – An Independent Prognostic Factor of Survival After Palliative Irradiation for Sino-nasal Cancer – PubMed

Medicine (Baltimore). 2021 May 7;100(18):e25692. doi: 10.1097/MD.0000000000025692.ABSTRACTINTRODUCTION: The relationship between chronic empyema and malignant tumors, most of which are lymphoma, has been recognized for many decades. Sarcomatoid carcinoma associated with chronic empyema is extremely rare, may metastasize to other organs in the early stage, and rapidly progresses to death. As far as we know, this was the first case report on sarcomatoid carcinoma associated chronic empyema.THE PATIENTS MAIN CONCERNS AND IMPORTANT CLINICAL FINDINGS: A 59-year-old man presented to our hospital with a 9-year history of chronic empyema and a chief complaint of left chest wall pain for 5 months. The…
Origen: Sarcomatoid carcinoma associated with chronic empyema and early lung and pleural metastases: A case report – PubMed

Chirurgia (Bucur). 2021 Mar-Apr;116(2):150-161. doi: 10.21614/chirurgia.116.2.150.ABSTRACTBreast cancer is one of the most severe health issues globally, but the therapy advancements and the constant adaptation of treatment protocols radically changed its prognoses. This article review of the literature from a surgical perspective, thus allowing for the optimum detection and placement of its role and benefits in the surgical and oncology therapeutics. The role of surgery becomes controversial, with sometimes «pretentious» techniques, hard to quantify benefits and challenges that require a thorough assessment prior to opting for surgery. Another interesting aspect is the relative lack of guidelines for such cases with an…
Origen: Palliative ("Toilet") Mammectomy, A Decision-Making Dilemma – Short Review – PubMed

Medicina (Kaunas). 2021 Apr 28;57(5):428. doi: 10.3390/medicina57050428.ABSTRACTBACKGROUND AND OBJECTIVES: Twenty percent of the patients affected with stage IV antropyloric stomach cancer are hospitalized with a gastric outlet obstruction syndrome (GOOS) requiring its resolution to improve the quality of life (QoL). We present our preliminary short- and mid-term results regarding the influence of endoscopic placement of self-expandable metal stent (SEMS) or open stomach-partitioning gastrojejunostomy in QoL.MATERIALS AND METHODS: In this prospective randomized longitudinal cohort trial, we randomly assigned 27 patients affected with stage IV antropyloric stomach cancer into two groups: Group 1 (13 patients) who underwent SEMS positioning and Group 2…
Origen: Palliative Surgery or Metallic Stent Positioning for Advanced Gastric Cancer: Differences in QOL – PubMed