Trials. 2021 Sep 16;22(1):635. doi: 10.1186/s13063-021-05546-5.ABSTRACTBACKGROUND: Palliative care is a medical specialty centered on improving the quality of life (QOL) of patients with complex or life-threatening illnesses. The need for palliative care is increasing and with that the rigorous testing of triage tools that can be used quickly and reliably to identify patients that may benefit from palliative care.METHODS: To that aim, we will conduct a two-armed stepped-wedge cluster randomized trial rolled out to two inpatient hospitals to evaluate whether a machine learning algorithm accurately identifies patients who may benefit from a comprehensive review by a palliative care specialist and…
Origen: Improving time to palliative care review with predictive modeling in an inpatient adult population: study protocol for a stepped-wedge, pragmatic randomized controlled trial – PubMed

Pneumologie. 2021 Sep;75(9):641-643. doi: 10.1055/a-1486-9057. Epub 2021 Sep 15.ABSTRACTTherapy of non-small cell lung cancer (NSCLC) should be based on biomarker test results in the palliative setting. To this end, testing of all patients in stage IV and in the future also in the earlier stages will be important. In a conference with the patronage of the German Cancer Society, the question of “reflex testing”, i. e. independently of tumor stage, was discussed but not deemed to be acceptable. The current report summarizes the results of the consensus conference and discusses possible paths to efficent biomarker testing in NSCLC.PMID:34525486 | DOI:10.1055/a-1486-9057
Origen: When to Test in Biomarker-stratified Therapy of Non-small Cell Lung Cancer – Biomarker-stratified Therapy of Non-small Cell Lung Cancer: When and What to Test? – PubMed

BMJ Open. 2021 Sep 13;11(9):e048696. doi: 10.1136/bmjopen-2021-048696.ABSTRACTINTRODUCTION: Approximately 20% of serious safety incidents involving palliative patients relate to medication. These are disproportionately reported when patients are in their usual residence when compared with hospital or hospice. While patient safety incident reporting systems can support professional learning, it is unclear whether these reports encompass patient and carer concerns with palliative medications or interpersonal safety.AIM: To explore and compare perceptions of (un)safe palliative medication management from patient, carer and professional perspectives in community, hospital and hospice settings.METHODS AND ANALYSIS: We will use an innovative mixed-methods study design combining systematic review searching techniques…
Origen: Mixed-methods study protocol: do national reporting and learning system medication incidents in palliative care reflect patient and carer concerns about medication management and safety? – PubMed

J Infect Dev Ctries. 2021 Aug 31;15(8):1094-1103. doi: 10.3855/jidc.14709.ABSTRACTINTRODUCTION: About 14% of COVID-19 patients experience severe symptoms and require hospitalization. Managing these patients could be challenging for limited-resource countries, such as Palestine. This study aimed to evaluate hospitalized severe COVID-19 patients’ treatment outcomes managed with supportive care and steroids.METHODOLOGY: This was a single-center observational retrospective cohort study that enrolled COVID-19 patients admitted to the “Martyrs medical military complex- COVID Hospital” in Palestine. The managing physicians manually collected data through chart reviews, including patients’ characteristics, complications, outcomes, and different management modalities. Continuous and categorical variables between those who were discharged alive…
Origen: The outcomes of severe COVID-19 pneumonia managed with supportive care in Palestine: an experience from a developing country – PubMed

Rev Esc Enferm USP. 2021 Sep 10;55:e20210159. doi: 10.1590/1980-220X-REEUSP-2021-0159. eCollection 2021.ABSTRACTOBJECTIVE: To discuss the evolution of research in cancer psychoneuroimmunology, the advances in the management of neuropsychological symptom clusters and their interface with mid-range theories, and practical applications in Nursing.METHOD: This is a theoretical-reflective study anchored in recent literature, as well as in the critical analysis of the authors.RESULTS: This is a promising field of investigation, which emphasizes the complexity and interaction of symptoms, the interrelationships among them, the factors influencing them, and their consequences. Subsidized by mid-range theories in Nursing, such as the Theory of Unpleasant Symptoms and the…
Origen: Psychoneuroimmunology and oncology nursing: a theoretical study – PubMed