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An interactive simulation tool for patient-specific clinical decision support in single-ventricle physiology.

Related Articles An interactive simulation tool for patient-specific clinical decision support in single-ventricle physiology. J Thorac Cardiovasc Surg. 2018 02;155(2):712-721 Authors: Conover T, Hlavacek AM, Migliavacca F, Kung E, Dorfman A, Figliola RS, Hsia TY, Modeling of Congenital Hearts Alliance (MOCHA) Investigators Abstract OBJECTIVE: Modeling of single-ventricle circulations has yielded important insights into their unique flow dynamics and physiology. Here we translated a state-of-the-art mathematical model into a patient-specific clinical decision support interactive Web-based simulation tool and show validation for all 3 stages of single-ventricular palliation. METHODS: Via the adoption a validated lumped parameter method, complete cardiovascular-pulmonary circulatory models of…
Origen: An interactive simulation tool for patient-specific clinical decision support in single-ventricle physiology. – PubMed

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Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer.

Related Articles Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer. J Clin Endocrinol Metab. 2017 Dec 01;102(12):4506-4514 Authors: Prasongsook N, Kumar A, Chintakuntlawar AV, Foote RL, Kasperbauer J, Molina J, Garces Y, Ma D, Wittich MAN, Rubin J, Richardson R, Morris J, Hay I, Fatourechi V, McIver B, Ryder M, Thompson G, Grant C, Richards M, Sebo TJ, Rivera M, Suman V, Jenkins SM, Smallridge RC, Bible KC Abstract Context: Historical outcomes in anaplastic thyroid cancer (ATC) have been dismal. Objective: To determine whether an initial intensive multimodal therapy (MMT) is associated with improved ATC survival. Design: MMT…
Origen: Survival in Response to Multimodal Therapy in Anaplastic Thyroid Cancer. – PubMed

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Treatment of Patients with Advanced Gastroesophageal Adenocarcinoma: Does Age Matter?

Related Articles Treatment of Patients with Advanced Gastroesophageal Adenocarcinoma: Does Age Matter? Drugs Aging. 2019 05;36(5):403-409 Authors: Lorenzen S, Hofheinz RD Abstract Gastroesophageal cancer is the fourth most frequent malignant disease and, despite significant advances in chemotherapy, the prognosis of unresectable or recurrent gastroesophageal cancer is poor. The majority of patients, nearly two-thirds, are over the age of 65 years at diagnosis. Elderly patients are a heterogeneous population and aging occurs at different rates in different individuals. The chronological age of a patient does not necessarily reflect the physiological age. However, elderly patients are more likely to have a number of…
Origen: Treatment of Patients with Advanced Gastroesophageal Adenocarcinoma: Does Age Matter? – PubMed

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Clinical Implications of C-Reactive Protein as a Prognostic Marker in Advanced Cancer Patients in Palliative Care Settings.

Related Articles Clinical Implications of C-Reactive Protein as a Prognostic Marker in Advanced Cancer Patients in Palliative Care Settings. J Pain Symptom Manage. 2016 May;51(5):860-7 Authors: Amano K, Maeda I, Morita T, Miura T, Inoue S, Ikenaga M, Matsumoto Y, Baba M, Sekine R, Yamaguchi T, Hirohashi T, Tajima T, Tatara R, Watanabe H, Otani H, Takigawa C, Matsuda Y, Nagaoka H, Mori M, Kinoshita H Abstract CONTEXT: Plasma C-reactive protein (CRP) levels are elevated in patients with advanced cancer. OBJECTIVES: To investigate CRP as a prognostic marker in palliative settings. METHODS: This multicenter prospective cohort study comprised 2426 patients.…
Origen: Clinical Implications of C-Reactive Protein as a Prognostic Marker in Advanced Cancer Patients in Palliative Care Settings. – PubMed

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Managing malignant pleural mesothelioma: experience and perceptions of health care professionals caring for people with mesothelioma.

Related Articles Managing malignant pleural mesothelioma: experience and perceptions of health care professionals caring for people with mesothelioma. Support Care Cancer. 2019 Sep;27(9):3509-3519 Authors: Warby A, Dhillon HM, Kao S, Vardy JL Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) has a poor prognosis and heavy symptom burden. Here, we investigate health professionals’ attitudes to management and decision-making in people with MPM. METHODS: Survey questions were based on previous interviews with health professionals, MPM patients, and caregivers. Surveys were sent to specialist doctors and nurses who treat MPM. RESULTS: Surveys were completed by 107 doctors and 19 nurses from January-September 2014. Most…
Origen: Managing malignant pleural mesothelioma: experience and perceptions of health care professionals caring for people with mesothelioma. – PubMed

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