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Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution?

Related Articles Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution? J Clin Oncol. 2018 02 10;36(5):483-491 Authors: Brown PD, Ahluwalia MS, Khan OH, Asher AL, Wefel JS, Gondi V Abstract An estimated 20% of patients with cancer will develop brain metastases. Approximately 200,000 individuals in the United States alone receive whole-brain radiotherapy (WBRT) each year to treat brain metastases. Historically, the prognosis of patients with brain metastases has been poor; however, with new therapies, this is changing. Because patients are living longer following the diagnosis and treatment of brain metastases, there has been rising concern about treatment-related toxicities associated with…
Origen: Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution? – PubMed

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Therapeutic developments in pancreatic cancer: current and future perspectives.

Related Articles Therapeutic developments in pancreatic cancer: current and future perspectives. Nat Rev Gastroenterol Hepatol. 2018 06;15(6):333-348 Authors: Neoptolemos JP, Kleeff J, Michl P, Costello E, Greenhalf W, Palmer DH Abstract The overall 5-year survival for pancreatic cancer has changed little over the past few decades, and pancreatic cancer is predicted to be the second leading cause of cancer-related mortality in the next decade in Western countries. The past few years, however, have seen improvements in first-line and second-line palliative therapies and considerable progress in increasing survival with adjuvant treatment. The use of biomarkers to help define treatment and the…
Origen: Therapeutic developments in pancreatic cancer: current and future perspectives. – PubMed

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Sarcoma in neurofibromatosis 2: case report and review of the literature.

Related Articles Sarcoma in neurofibromatosis 2: case report and review of the literature. Fam Cancer. 2019 01;18(1):97-100 Authors: Linder C, Smith MJ, Bulman M, Wallace A, Freemont AJ, Mangham DC, Evans DGR Abstract Neurofibromatosis type 2 (NF2) is associated with the development of several types of benign nervous system tumours, while malignancies are rare. We report a 22-year-old man who presented with retroperitoneal and spinal high-grade sarcomas with epithelial features. Samples showed a mixed epithelioid and spindled cell content with little associated matrix and inconclusive immunochemistry. Genetic analysis of a schwannoma and matched blood samples demonstrated a constitutional de novo…
Origen: Sarcoma in neurofibromatosis 2: case report and review of the literature. – PubMed

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Outcomes of collaborative and interdisciplinary palliative education for health care assistants: A qualitative metasummary.

Related Articles Outcomes of collaborative and interdisciplinary palliative education for health care assistants: A qualitative metasummary. J Nurs Manag. 2019 Apr;27(3):461-481 Authors: Friesen L, Andersen E Abstract AIM: To explore collaborative and interdisciplinary palliative educational strategies and corresponding outcomes for health care assistants. BACKGROUND: Health care assistants are frontline staff who provide almost all hands-on care to seniors. Health care managers are responsible to provide ongoing support and a working environment conducive to health care assistants’ abilities to provide quality, safe, evidence-based care. EVALUATION: A Qualitative metasummary of collaborative and interdisciplinary teaching strategies was conducted following guidelines developed by Sandelowski…
Origen: Outcomes of collaborative and interdisciplinary palliative education for health care assistants: A qualitative metasummary. – PubMed

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