Anticancer Res. 2026 Feb;46(2):1153-1165. doi: 10.21873/anticanres.18018.ABSTRACTBACKGROUND/AIM: Treatment of cancers known to be positive for the nuclear progesterone receptor (nPR), e.g., breast, ovarian, and endometrial cancers with PR modulators/antagonists, e.g., mifepristone, have not shown impressive improvement in palliative or longevity benefits. In contrast, several case reports showed considerable palliation and/or extension of life using mifepristone treatment for various advanced cancers devoid of the nPR. The aim of this study was to determine whether mifepristone therapy could provide improved quality of life in a patient with breast cancer considered terminal based on extensive brain and lung metastases in which the estrogen receptor…
Origen: Marked Palliative Benefits Seen With Treatment of Very Advanced Breast Cancer With the Progesterone Receptor Modulator Mifepristone – PubMed

Prim Health Care Res Dev. 2026 Jan 30;27:e15. doi: 10.1017/S1463423625100777.ABSTRACTOBJECTIVES: Palliative care development in primary care is crucial worldwide. This study reports on the secondary outcomes of a study that evaluated whether a complex intervention in primary care for patients with palliative care needs impacted their healthcare utilization.METHODS: A before-after study was conducted with family physicians and patients with palliative care needs. Physicians received palliative care training and implemented a new primary palliative care consultation model. Healthcare utilization in the 12 weeks before, during, and after the intervention was compared.RESULTS: We analysed healthcare utilization for 33 patients with advanced disease.…
Origen: Impact of a complex intervention in primary care for patients with palliative care needs in their healthcare utilization: a before-after study – PubMed

Front Public Health. 2026 Jan 13;13:1690798. doi: 10.3389/fpubh.2025.1690798. eCollection 2025.ABSTRACTMemory making is a core component of holistic paediatric palliative care. However, traditional artifact-based keepsakes (e.g., handprints) are often passive and lack the developmental and cultural sensitivity needed for meaningful engagement. A more participatory, narrative-based, multimedia approach, such as digital storytelling, is therefore required. Following the ADAPT framework (Steps 1-2: Intervention-Context Fit and Planning Adaptations), this study adapted a U.S. developed digital storytelling intervention for children with life-limiting and life-threatening conditions and their families in Ireland. Methods included a literature review, stakeholder consultations (n = 21), co-production workshops, and the development…
Origen: Digital storytelling as a memory-making intervention for children and families in paediatric palliative care in Ireland: an adaptation study – PubMed

Br J Hosp Med (Lond). 2026 Jan 26;87(1):50391. doi: 10.31083/BJHM50391.ABSTRACTAIMS/BACKGROUND: With the growing need for high-quality end-of-life care in China, this study aimed to evaluate the practical palliative care skills of nurses across 17 pilot institutions in Hangzhou, identify the key factors influencing these skills, and explore their interrelationships. The ultimate goal was to inform the development of a targeted training and assessment system that can support and enhance palliative care team development in China.METHODS: This study used a convergent mixed-methods design integrating quantitative and qualitative approaches. From February to May 2022, 723 nurses from 17 palliative care pilot institutions…
Origen: A Mixed-Methods Study on the Current Situation and Factors Influencing Nurses' Practice of Palliative Care in Hangzhou, China – PubMed

Br J Community Nurs. 2026 Feb 2;31(2):82. doi: 10.12968/bjcn.2026.0008. Epub 2026 Jan 29.ABSTRACTThe author discusses the symbolism of Valentine’s Day and how it may intensify emotional distress for individuals living with life-limiting or terminal illness, their partners and those experiencing bereavement. The article highlights the importance of recognising the emotional significance of culturally significant events and their potential to reactivate grief responses.PMID:41609625 | DOI:10.12968/bjcn.2026.0008
Origen: Intimacy in palliative care – PubMed